Chitosan-DNA nanoparticles enhanced the immunogenicity of multivalent DNA vaccination on mice against Trueperella pyogenes infection
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چکیده
منابع مشابه
Chitosan-DNA nanoparticles enhanced the immunogenicity of multivalent DNA vaccination on mice against Trueperella pyogenes infection
BACKGROUND Trueperella pyogenes is a commensal and opportunistic pathogen that normally causes mastitis, liver abscesses and pneumonia of economically important livestock. To develop efficacious and potent vaccine against T. pyogenes, chimeric gene DNA vaccines were constructed and encapsulated in chitosan nanoparticles (pPCFN-CpG-CS-NPs). RESULTS The pPCFN-CpG-CS-NPs consists of the plo, cbp...
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ژورنال
عنوان ژورنال: Journal of Nanobiotechnology
سال: 2018
ISSN: 1477-3155
DOI: 10.1186/s12951-018-0337-2